Spurs boss Popovich will lead Team USA in Tokyo after replacing Mike Krzyzewski following the 2016 Games.
And Popovich's presence could be enough to tempt three-time NBA champion James — who sat out Rio 2016 — to play in the Japanese capital, when he will be 35 years old.
"It factors a lot," James said before Saturday's clash, having called Popovich the greatest coach of all-time recently.
"I've said that before. He's just a great mastermind of the game of basketball."
James has played under five head coaches throughout his illustrious career — Tyronn Lue, David Blatt, Erik Spoelstra, Mike Brown and Paul Silas.
Asked if he was jealous of players like Tim Duncan, Paul Parker and Manu Ginobili, who have spent their entire careers under Popovich, James said he has "never really thought about it."
"If it would've happened it would've been a pretty cool thing, but it hasn't, and I really haven't put too much into it," James said. "Look at the landscape of the league; it changes so much. It was fortunate enough that Gregg had been such a great coach for so long, but he was brought to a team who had a franchise player in David [Robinson] at that point and time. ... But they've been winning for so long, they've had no reason to ever think about not believing in Gregg Popovich.
"We know in our league that it's a revolving door at times, with coaches and players and things of that nature, but for me I've played for some really good coaches in my career and I'm not envious of none of that."